Detalhe da pesquisa
1.
SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species.
Cell
; 177(3): 622-638.e22, 2019 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31002797
2.
Tracking break-induced replication shows that it stalls at roadblocks.
Nature
; 590(7847): 655-659, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33473214
3.
Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence.
Mol Cell
; 73(4): 684-698.e8, 2019 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30773298
4.
Mammalian aging driven by transcription going awry.
Trends Genet
; 39(10): 715-716, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37419698
5.
Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis.
Cell
; 136(6): 1073-84, 2009 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-19303850
6.
H3K36 methylation promotes longevity by enhancing transcriptional fidelity.
Genes Dev
; 29(13): 1362-76, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26159996
7.
Genetic screen identifies adaptive aneuploidy as a key mediator of ER stress resistance in yeast.
Proc Natl Acad Sci U S A
; 115(38): 9586-9591, 2018 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30185560
8.
Loss of chromatin structural integrity is a source of stress during aging.
Hum Genet
; 139(3): 371-380, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31900586
9.
Loss of Nat4 and its associated histone H4 N-terminal acetylation mediates calorie restriction-induced longevity.
EMBO Rep
; 17(12): 1829-1843, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27799288
10.
High-throughput analysis of yeast replicative aging using a microfluidic system.
Proc Natl Acad Sci U S A
; 112(30): 9364-9, 2015 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26170317
11.
MYST protein acetyltransferase activity requires active site lysine autoacetylation.
EMBO J
; 31(1): 58-70, 2012 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22020126
12.
Histone methylation and aging: lessons learned from model systems.
Biochim Biophys Acta
; 1839(12): 1454-62, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24859460
13.
Histone H4 lysine 16 acetylation regulates cellular lifespan.
Nature
; 459(7248): 802-7, 2009 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-19516333
14.
Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction.
EMBO J
; 29(1): 158-70, 2010 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19875981
15.
The controversial world of sirtuins.
Drug Discov Today Technol
; 12: e9-e17, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25027380
16.
SIRT1 safeguards adipogenic differentiation by orchestrating anti-oxidative responses and suppressing cellular senescence.
Geroscience
; 46(1): 1107-1127, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37420111
17.
Yeast EndoG prevents genome instability by degrading cytoplasmic DNA.
Res Sq
; 2024 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38260641
18.
Yeast EndoG prevents genome instability by degrading cytoplasmic DNA.
bioRxiv
; 2023 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38168242
19.
Loosening chromatin and dysregulated transcription: a perspective on cryptic transcription during mammalian aging.
Brief Funct Genomics
; 21(1): 56-61, 2022 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34050364
20.
Histone H4 lysine 20 of Saccharomyces cerevisiae is monomethylated and functions in subtelomeric silencing.
Biochemistry
; 50(48): 10473-83, 2011 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21985125